| Sabato 11/12/21 | Veres Rivne | 1 - 1 | Rukh Lviv | |
|---|---|---|---|---|
| Sabato 04/12/21 | Rukh Lviv | 0 - 0 | Vorskla Poltava | |
| Domenica 28/11/21 | Rukh Lviv | 2 - 0 | Metalist Kharkiv | |
| Sabato 20/11/21 | Shakhtar Donetsk | 2 - 0 | Rukh Lviv | |
| Sabato 06/11/21 | Chernomorets Odessa | 4 - 3 | Rukh Lviv | |
| Domenica 31/10/21 | Rukh Lviv | 0 - 0 | Oleksandria | |
| Domenica 24/10/21 | Rukh Lviv | 2 - 2 | Minaj | |
| Venerdi 01/10/21 | Mariupol | 0 - 2 | Rukh Lviv | |
| Sabato 25/09/21 | Rukh Lviv | 0 - 2 | Dynamo Kiev | |
| Venerdi 17/09/21 | FK Desna Chernihiv | 1 - 0 | Rukh Lviv | |
| Sabato 11/09/21 | Rukh Lviv | 1 - 1 | Zorya | |
| Domenica 29/08/21 | Rukh Lviv | 1 - 0 | FK Lviv | |
| Sabato 21/08/21 | SK Dnipro-1 | 2 - 0 | Rukh Lviv | |
| Domenica 15/08/21 | Kolos Kovalyovka | 1 - 1 | Rukh Lviv | |
| Sabato 07/08/21 | Rukh Lviv | 2 - 1 | Veres Rivne | |
| Domenica 01/08/21 | Vorskla Poltava | 2 - 0 | Rukh Lviv | |
| Domenica 25/07/21 | Metalist Kharkiv | 2 - 1 | Rukh Lviv | |
| Domenica 09/05/21 | SK Dnipro-1 | 1 - 1 | Rukh Lviv | |
| Giovedi 06/05/21 | Rukh Lviv | 3 - 0 | Olimpik Donetsk | |
| Domenica 02/05/21 | Rukh Lviv | 2 - 1 | Oleksandria |