| Venerdi 10/12/21 | Mariupol | 0 - 3 | SK Dnipro-1 | |
|---|---|---|---|---|
| Domenica 05/12/21 | FK Desna Chernihiv | 3 - 3 | Mariupol | |
| Venerdi 26/11/21 | Mariupol | 0 - 1 | FK Lviv | |
| Domenica 21/11/21 | Vorskla Poltava | 5 - 1 | Mariupol | |
| Sabato 06/11/21 | Minaj | 0 - 2 | Mariupol | |
| Sabato 30/10/21 | Mariupol | 2 - 3 | Dynamo Kiev | |
| Sabato 23/10/21 | Veres Rivne | 2 - 0 | Mariupol | |
| Sabato 16/10/21 | Mariupol | 1 - 2 | Metalist Kharkiv | |
| Venerdi 01/10/21 | Mariupol | 0 - 2 | Rukh Lviv | |
| Sabato 25/09/21 | Oleksandria | 2 - 1 | Mariupol | |
| Sabato 18/09/21 | Mariupol | 0 - 5 | Shakhtar Donetsk | |
| Domenica 12/09/21 | Kolos Kovalyovka | 1 - 3 | Mariupol | |
| Sabato 28/08/21 | Inhulets | 3 - 0 | Mariupol | |
| Domenica 22/08/21 | Mariupol | 3 - 4 | Zorya | |
| Lunedi 16/08/21 | Mariupol | 2 - 3 | Chernomorets Odessa | |
| Sabato 07/08/21 | SK Dnipro-1 | 2 - 1 | Mariupol | |
| Domenica 01/08/21 | Mariupol | 1 - 2 | FK Desna Chernihiv | |
| Venerdi 23/07/21 | FK Lviv | 1 - 1 | Mariupol | |
| Domenica 09/05/21 | Mariupol | 4 - 1 | FK Desna Chernihiv | |
| Mercoledi 05/05/21 | Dynamo Kiev | 0 - 0 | Mariupol |